Research Areas

Clinical Focus

    • Attention deficit hyperactivity disorder (ADHD) is one of the most common childhood disorders and can continue through adolescence and adulthood. Symptoms include difficulty staying focused and paying attention, difficulty controlling behavior, and hyperactivity (over-activity).

    • The set of all mental abilities and processes related to knowledge: attention, memory and working memory, judgment and evaluation, reasoning and “computation”, problem solving and decision making, comprehension and production of language, etc.

    • A mood disorder that causes a persistent feeling of sadness and loss of interest. Also called major depression, major depressive disorder or clinicaldepression, it affects how you feel, think and behave and can lead to a variety of emotional and physical problems.

    • A state of abnormal muscle tone resulting in muscular spasm and abnormal posture, typically due to neurological disease or a side effect of drug therapy.

    • A neurological disorder marked by sudden recurrent episodes of sensory disturbance, loss of consciousness, or convulsions, associated with abnormal electrical activity in the brain.

    • Characterized by unreasonable thoughts and fears (obsessions) that lead you to do repetitive behaviors (compulsions).

    • A progressive disease of the nervous system marked by tremor, muscular rigidity, and slow, imprecise movement, chiefly affecting middle-aged and elderly people. It is associated with degeneration of the basal ganglia of the brain and a deficiency of the neurotransmitter dopamine.

    • A condition of persistent mental and emotional stress occurring as a result of injury or severe psychological shock, typically involving disturbance of sleep and constant vivid recall of the experience, with dulled responses to others and to the outside world.

    • A long-term mental disorder of a type involving a breakdown in the relation between thought, emotion, and behavior, leading to faulty perception, inappropriate actions and feelings, withdrawal from reality and personal relationships into fantasy and delusion, and a sense of mental fragmentation.

    Technology Development

    A DARPA funded novel wireless battery-less implantable neuromodulation device is being developed at UCLA through collaboration between Departments of Neurosurgery, Engineering and Psychiatry and Biobehavioral Sciences. The new device can record single-unit, local field, and intracranial EEG signals in a closed loop manner that can trigger stimulation to single or a combination of up to 32 micro- and macro-electrodes. This novel technology has wide implications for improved treatment of neuropsychiatric disorders.

    Understanding Brain Functions