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Our goal is to understand how patterns of neural activity arise in prefrontal circuits and how those patterns influence behavior. A major focus of the lab is on dopaminergic projections from the ventral tegmental area (VTA) to the medial prefrontal cortex (mPFC), which regulate critical functions that are frequently disrupted in psychiatric disorders.
My laboratory focuses on the function of neurotransmitter transporters, the proteins responsible for transporting neurotransmitters such as dopamine and serotonin across biological membranes. Using a variety of molecular and genetic techniques, we study how neurotransmitter transport is regulated in cultured cells and in the model organism Drosophila, and how changes in transporter function may influence behavior.
Our focus is on treatment of refractory depression, OCD and comorbid OCD-Depression by using multimodal treatment options of Transcranial Magnetic Stimulation (TMS), advanced pharmacology and Exposure and Response Prevention therapy.
The Laboratory of Neuromodulation and Neuroimaging focuses on development of invasive and non-invasive methodologies to restore cognitive functions such as learning, memory and spatial navigation.
Our lab investigates human brain functions in health and disease using non invasive techniques. We use Magnetic Resonance Imaging (MRI) to image brain structure and functions. We also stimulate the brain painlessly and modulate its activity with Transcranial Magnetic Stimulation (TMS) and Transcranial Direct Current Stimulation (tDCS).